Babuška Forum: Actionable digital twins for patients who are not average

Talk Abstract

Over the last decade our team has developed a set of partial differential equations that capture key features of tumor dynamics related to cell migration, proliferation, treatment response, and tissue mechanical properties. These models can be calibrated with widely-available medical imaging data to accurately predict the spatio-temporal changes of solid tumors in response to both radiation and systemic therapies. We will briefly summarize those results, and then show how these models can power digital twins to identify alternative therapeutic regimens that may outperform the standard-of-care interventions.